Publications scientifiques

HIF-1α-Driven SLC37A2/SLC37A3/G6PC3 Transcriptional reprogramming shapes glioblastoma stemness in 3D neurospheres

Fallah A, Zgheib A, Danalache BA, Eliopoulos N, ANNABI B.

CRISPR-based chemogenomic profiling reveals redox vulnerabilities to epigallocatechin-3-gallate and green tea polyphenol extract

Akla N, Boudah A, Bertomeu T, Chatr-aryamontri A, Desjarlais M, ANNABI B.

Étude CRISPR révélant les cibles cellulaires exactes de l'EGCG : le thé vert exploite des déséquilibres redox spécifiques aux cellules cancéreuses, épargnant les cellules saines.

Disrupting the TGF-β-regulated epithelial-mesenchymal transition, apoptotic and autophagic phenotypes of 3D glioblastoma spheroids via glycolytic inhibition

Payet-Desruisseaux M, Zgheib A, Danalache BA, Desjarlais M, ANNABI B.

Probing into the chemopreventive properties of synthetic 1,3,6-tri-O-galloyl-α-D-glucose (α-TGG) against glioblastoma and triple-negative breast cancer-derived cell models

Veilleux C, Khalifa J, Zgheib A, Konan AS, Gaudreault R, ANNABI B.

Quercetin targets TGFβ-primed human MDA-MB-231 triple-negative breast cancer cells, linking epithelial-mesenchymal transition to cell senescence and fibrosis

Pepin SK, Zgheib A, Roy ME, ANNABI B.

La quercétine (présente dans les oignons) cible les cellules du cancer du sein triple-négatif — le sous-type le plus agressif — en bloquant la voie TGF-β impliquée dans les métastases.

A SORT1/EGFR molecular interplay as a prognostic biomarker in glioblastoma vasculogenic mimicry: implications in the transcriptional regulation of cancer stemness and drug resistance

Roy ME, Zgheib A, Eliopoulos N, ANNABI B.

Hippo pathway suppression reprograms TNFα-primed glioblastoma extracellular vesicles cargo to drive mesenchymal stem/stromal cells vasculogenic mimicry

Zilinski R, Konan AS, Zgheib A, Eliopoulos N, Boudreau LH, ANNABI B.

Chemopreventive targeting of oncogenic stemness: EGCG-mediated suppression of the HIF-1α-PPARg-cancer stem cells transcriptional signature in 3D glioblastoma spheroids

Fallah A, Payet-Desruisseaux M, Zgheib A, Danalache BA, Eliopoulos N, ANNABI B.

L'EGCG cible spécifiquement les cellules souches du glioblastome — les plus résistantes aux traitements — en bloquant leurs voies de survie oncogéniques.

Synthetic 1,3,6-tri-O-galloyl-α-D-glucose mimics the Hippo pathway inhibitor VT107 in suppressing concanavalin A-induced inflammation in human glioblastoma cells

Konan AS, Zilinski R, Tadrous M, Zgheib A, Gaudreault R, ANNABI B.

Transcriptional regulation of CYR61 and CTGF by LM98: a synthetic YAP-TEAD inhibitor that targets in-vitro vasculogenic mimicry in glioblastoma cells

Roy ME, Veilleux C, Paquin A, Gagnon A, ANNABI B.

The chemopreventive impact of diet-derived phytochemicals on the adipose tissue and breast tumor microenvironment secretome

Akla N, Veilleux C, ANNABI B.

Revue sur l'impact chimiopréventif des phytochimiques : l'EGCG et d'autres composés alimentaires inhibent G6PT, une cible métabolique clé dans les cellules cancéreuses.

A role for the Hippo/YAP1 pathway in the regulation of in vitro vasculogenic mimicry in glioblastoma cells

Roy ME, Elimam R, Zgheib A, ANNABI B.

A molecular signature for the G6PC3 / SLC37A2 / SLC37A4 interactors in glioblastoma disease progression and in the acquisition of a brain cancer stem cell phenotype

Torabidastgerdooei S, Roy ME, ANNABI B.

Epigallocatechin-3-Gallate Prevents the Acquisition of a Cancer Stem Cell Phenotype in Ovarian Cancer Tumorspheres through the Inhibition of Src/JAK/STAT3 Signaling

Rodriguez Torres S, Gresseau L, Benhamida M, Fernandez-Marrero Y, ANNABI B.

L'EGCG du thé vert empêche les cellules du cancer de l'ovaire d'acquérir une résistance au carboplatine (chimiothérapie de référence), suggérant une synergie thérapeutique.

EGCG inhibits the inflammation and senescence inducing properties of MDA-MB-231 triple-negative breast cancer (TNBC) cells-derived extracellular vesicles in human adipose-derived mesenchymal stem cells

Gonzalez Suarez N, Fernandez-Marrero Y, Hébert M, Roy ME, Boudreau LH, ANNABI B.

Gut microbiota influence anastomotic healing in colorectal cancer surgery through modulation of mucosal pro-inflammatory cytokines

Hajjar R, Gonzalez E, Oliero M, Alaoui AA, Fragoso G, Calvé A, Vennin Rendos H, Djediai S, Cuisiniere T, Laplante P, Gerkins C, Ajayi AS, Diop K, Taleb N, Thérien S, Shampaert F, Alratrout H, Dagbert

EGCG Prevents the Transcriptional Reprogramming of an Inflammatory and Immune-Suppressive Molecular Signature in Macrophage-like Differentiated Human HL60 Promyelocytic Leukemia Cells

Kassouri C, Rodriguez Torres S, Gonzalez Suarez N, Duhamel S, ANNABI B.

EGCG Prevents the Onset of an Inflammatory and Cancer-Associated Adipocyte-like Phenotype in Adipose-Derived Mesenchymal Stem/Stromal Cells in Response to the Triple-Negative Breast Cancer Secretome

Gonzalez Suarez N, Fernandez-Marrero Y, Torabidastgerdooei S, ANNABI B.

A signaling crosstalk links Snail to the 37/67 kDa laminin-1 receptor ribosomal protein SA and regulates the acquisition of a cancer stem cell molecular signature in U87 glioblastoma neurospheres

Gresseau L, Roy ME, Duhamel S, ANNABI B

MT1-MMP expression levels and catalytic functions dictate LDL receptor-related protein-1 ligand internalization capacity in U87 glioblastoma cells

Pratt J, Haidara K, ANNABI B

MT1-MMP Cooperates with TGF-b Receptor-Mediated Signaling to Trigger SNAIL and Induce Epithelial-to-Mesenchymal-like Transition in U87 Glioblastoma Cells

Djediai S, Gonzalez Suarez N, El Cheikh-Hussein L, Rodriguez Torres S, Gresseau L, Dhayne S, Joly-Lopez Z, ANNABI B

Functional targeting of the TGF- βR1 kinase domain and downstream signaling: A role for the galloyl moiety of green tea-derived catechins in ES-2 ovarian clear cell carcinoma

Sicard AA, Gonzalez Suarez N, Cappadocia L, ANNABI B

Diet-Derived Gallated Catechins Prevent TGF-b-Mediated Epithelial- Mesenchymal Transition, Cell Migration and Vasculogenic Mimicry in Chemosensitive ES-2 Ovarian Cancer Cells

Sicard AA, Dao T, Suarez NG, ANNABI B

EGCG inhibits adipose-derived mesenchymal stem cells differentiation into adipocytes and prevents a STAT3-mediated paracrine oncogenic control of triple-negative breast cancer cell invasive phenotype

González Suárez N, Rodriguez Torres S, Ouanouki A, El Cheikh-Hussein L, ANNABI B

Machine learning algorithms for the structure-to-function analysis of diet-derived catechins-mediated targeting of in vitro vasculogenic mimicry

Uthamacumaran A, Gonzalez Suarez N, Baniré Diallo A, ANNABI B

Improvement of colonic anastomotic healing and surgical recovery with perioperative supplementation of inulin and galacto-oligosaccharides

Hajjar R, Oliero M, Cuisiniere T, Fragoso G, Calvé A, Djediai S, ANNABI B, Richard CS, Santos MM

Pharmacological targeting of neurotensin response by diet-derived EGCG in macrophage-differentiated HL-60 promyelocytic leukemia cells

Dao T, Salahuddin S, Charfi C, Sicard AA, Jenabian MA, ANNABI B

[10]-Gingerol improves doxorubicin anticancer activity and decreases its side effects in triple negative breast cancer models

Martin AC, Tomasin R, Luna-Dulcey L, Graminha AE, Naves MA, Gomes Teles RH, da Silva VD, da Silva JA, Vieira PC, ANNABI B, Cominetti MR

Periostin, a signal transduction intermediate in TGF-β-induced EMT in U-87MG human glioblastoma cells, and its inhibition by anthocyanidins

Ouanouki A., Lamy S., Annabi B.

Biophysical evidence for differential gallated green tea catechins binding to membrane type-1 matrix metalloproteinase and its interactors

Djerir D, Iddir M, Bourgault S, Lamy S, Annabi B

Antiproliferative efficacy of elderberries and elderflowers (Sambucus canadensis) on glioma and brain endothelial cells under normoxic and hypoxic conditions­

Lamy S, Muhire É, Annabi B.

Cavin-2 Functions as a Suppressive Regulator in TNF-induced Mesenchymal Stromal Cell Inflammation and Angiogenic Phenotypes

Annabi B, Zgheib A, Annabi B.

Anthocyanidins inhibit epithelial-mesenchymal transition through a TGFβ/Smad2 signaling pathway in glioblastoma cells

Ouanouki A, Lamy S, Annabi B.

Impact of Concanavalin-A-Mediated Cytoskeleton Disruption on Low-Density Lipoprotein Receptor-Related Protein-1 Internalization and Cell Surface Expression in Glioblastomas

Nanni SB, Pratt J, Beauchemin D, Haidara K, Annabi B.

Olive oil compounds inhibit the paracrine regulation of TNF-a-induced endothelial cell migration through reduced glioblastoma cell cyclooxygenase-2 expression

Lamy S, Ben Saad A, Zgheib A, Annabi B.

Les composés phénoliques de l'huile d'olive (oléocanthal, hydroxytyrosol) inhibent COX-2 dans des cellules de glioblastome humain — un mécanisme similaire à l'ibuprofène.

Evidence of MTCBP-1 interaction with the cytoplasmic domain of MT1-MMP: Implications in the autophagy cell index of high-grade glioblastoma

Pratt J, Iddir M, Bourgault S, Annabi B.

Membrane type-1 matrix metalloproteinase-regulated autophagy : A role in brain cancer chemoresistance

Pratt A, Coady M, Annabi B.

Biphasic effects of luteolin on interleukin-1b-induced cyclooxygenase-2 expression in glioblastoma cells

Lamy S, Moldovan PL, Ben Saad A, Annabi B.

A Role for the Cavin-3/Matrix Metalloproteinase-9 Signaling Axis in the Regulation of PMA-Activated Human HT1080 Fibrosarcoma Cell Neoplastic Phenotype

Toufaily C, Charfi C, Annabi B, Annabi B.

Transcriptional targeting of sphingosine-1-phosphate receptor S1P2 by epigallocatechin-3-gallate prevents sphingosine-1-phosphate-mediated signaling in macrophage-differentiated HL-60 promyelomonocytic leukemia cells

Chokor R, Lamy S, Annabi B

Induction of autophagy biomarker BNIP3 requires a JAK2/STAT3 and MT1-MMP signaling interplay in Concanavalin-A-activated U87 glioblastoma cells

Pratt J, Annabi B.

Olive oil compounds inhibit vascular endothelial growth factor receptor-2 phosphorylation

Lamy S, Ouanouki A, Béliveau R, Desrosiers RR.

Les polyphénols de l'olive bloquent VEGFR-2, le principal récepteur impliqué dans la formation de nouveaux vaisseaux sanguins qui alimentent les tumeurs.

Tetracycline Derivative Minocycline Inhibits Autophagy and Inflammation in Concanavalin-A-Activated Human Hepatoma Cells

Desjarlais M, Pratt J, Lounis A, Mounier C, Haidara K, Annabi B

Mesenchymal stromal cell ciliogenesis is abrogated in response to tumor necrosis factor-α and requires NF-κB signaling

Vézina A, Vaillancourt-Jean E, Albarao S, Annabi B

MT1-MMP expression level status dictates the in vitro action of lupeol on inflammatory biomarkers MMP-9 and COX-2 in medulloblastoma cells

Annabi B., Vaillancourt-Jean, E., Béliveau R.

Epigallocatechin gallate targeting of membrane type 1 matrix metalloproteinase-mediated Src and Janus kinase/signal transducers and activators of transcription 3 signaling inhibits transcription of colony-stimulating factors 2 and 3 in mesenchymal stromal cells

Zgheib A, Lamy S, Annabi B.

EGCG targeting efficacy of NF-κB downstream gene products is dictated by the monocytic/macrophagic differentiation status of promyelocytic leukemia cells

Vézina A, Chokor R, Annabi B.

Concanavalin-A-induced autophagy biomarkers requires membrane type-1 matrix metalloproteinase intracellular signaling in glioblastoma cells

Pratt J, Roy R, Annabi B.

Diet-derived polyphenols inhibit angiogenesis by modulating the interleukin-6/STAT3 pathway

Lamy S, Akla N, Ouanouki A, Lord-Dufour S, Béliveau R

Resveratrol targeting of carcinogen-induced brain endothelial cell inflammation biomarkers MMP-9 and COX-2 is Sirt1-independent

Annabi B, Lord-Dufour S, Vézina A, Béliveau R

Quercetin abrogates IL-6/STAT3 signaling and inhibits glioblastoma cell line growth and migration

Michaud-Levesque J, Bousquet-Gagnon N, Béliveau R

Colorectal cancer prevention through dietary and lifestyle modifications

Gingras D, Beliveau R

Revue complète sur la prévention du cancer colorectal par l'alimentation : les crucifères, les fruits rouges et le thé vert agissent sur le microenvironnement tumoral pour empêcher la progression.

A role for MT1-MMP as a cell death sensor/effector through the regulation of endoplasmic reticulum stress in U87 glioblastoma cells

Proulx-Bonneau S., Pratt J. & Annabi B.

Flavonoids targeting of IκB phosphorylation abrogates carcinogen-induced MMP-9 and COX-2 expression in human brain endothelial cells

Tahanian T., Arguello-Sanchez L., Shiao TC., Roy R. & Annabi B.

Low intracellular ATP levels exacerbate carcinogen-induced inflammatory stress response and inhibit in vitro tubulogenesis in human brain endothelial cells

Tahanian E., Peiro S. & Annabi B.

Curcumin inhibits tumor growth and angiogenesis in glioblastoma xenografts

Perry MC, Demeule M, Régina A, Moumdjian R, Béliveau R

La curcumine provoque une régression significative de xénogreffes de glioblastome chez la souris, ouvrant la voie à des essais cliniques en neuro-oncologie.

Inhibition of membrane-type 1 matrix metalloproteinase tyrosine phosphorylation blocks tumor progression in mice

Nyalendo C, Sartelet H, Gingras D, Béliveau R

Propranolol suppresses angiogenesis in vitro: inhibition of proliferation, migration, and differentiation of endothelial cells

Lamy S, Lachambre M-P, Lord-Dufour S, Béliveau R

Pharmacological targeting of b-adrenergic receptor functions abrogates carcinogen-mediated MMP-9 secretion through NF-kB signalling in medulloblastoma cells OncoTargets and Therapy 3:219-226

Annabi B, Vaillancourt-Jean E, Weil AG & Béliveau R

The lectin concanavalin-A signals MT1-MMP catalytic independent induction of COX-2 through an IKKg/NF-kB-dependent pathway

Sina A., Proulx-Bonneau S., Roy A., Poliquin L., Cao J. & Annabi B.

Modulation of invasive properties of CD133(+) glioblastoma stem cells : A role for MT1-MMP in bioactive lysophospholipid signaling Molecular Carcinogenesis 48(10):910-919

Annabi B, Lachambre MP, Plouffe K, Sartelet H & Béliveau R

A MT1-MMP/NF-kB signaling axis as a checkpoint controller of COX-2 expression in CD133(+) U87 glioblastoma cells

Annabi B, Laflamme C, Sina A, Lachambre MP, Béliveau R

The Flavonols Quercetin, Kaempferol, and Myricetin Inhibit Hepatocyte Growth Factor-Induced Medulloblastoma Cell Migration J

Labbé D, Provençal M, Lamy S, Boivin D, Gingras D and Béliveau R

c-Met activation in medulloblastoma induces tissue factor expression and activity: effects on cell migration

Provençal M, Labbé D, Veitch R, Boivin D, Rivard G-E, Sartelet H, Robitaille Y, Gingras D and Béliveau R

Tissue factor mediates the HGF/MET-induced anti-apoptotic pathway in DAOY medulloblastoma cells

Provençal M, Labbé D, Veitch R, Boivin D, Rivard GE, Gingras D, Béliveau R

The stem cell marker CD133 (prominin-1) is phosphorylated on cytoplasmic tyrosine-828 and tyrosine-852 by Src and Fyn tyrosine kinases

Boivin D, Labbé D, Fontaine N, Lamy S, Beaulieu E, Gingras D, Béliveau R

Antiproliferative and antioxidant activities of common vegetables: A comparative study

Boivin D, Lamy S, Lord-Dufour S, Jackson J, Beaulieu E, Côté M, Moghrabi A, Barrette S, Gingras D, Béliveau R

Étude comparative : l'ail, le poireau et les oignons présentent l'activité antiproliférative la plus forte parmi les légumes courants — confirmant leur rôle central dans la prévention du cancer.

Delphinidin, a dietary anthocyanidin, inhibits platelet derived growth fator ligand/receptor (PDGF/PDGFR) signaling

Lamy S, Beaulieu E, Labbé D, Bédard V, Moghrabi A, Barrette S, Gingras D, Béliveau R

La delphinidin, anthocyanidin des fruits rouges (myrtilles, sureau), inhibe le récepteur PDGF, un acteur clé dans la croissance tumorale et l'angiogenèse.

Regulation of Brain Endothelial Cells Migration and Angiogenesis by P-glycoprotein/Caveolin-1 Interaction

Barakat S, Turcotte S, Demeule M, Lachambre MP, Régina A, Baggetto LG, Béliveau R

The dietary flavones apigenin and luteolin impair smooth muscle cell migration and VEGF expression through inhibition of PDGFR-? phosphorylation

Lamy S, Bédard V, Sartelet H, Barthomeuf C, Gingras D, Béliveau R

Silencing of the MT1-MMP / G6PT axis suppresses calcium mobilization by sphingosine-1-phosphate in glioblastoma cells

Fortier S., Labelle D., Sina A., Moreau R. & Annabi B.

The diet-derived sulforaphane inhibits matrix metalloproteinase-9-activated human brain microvascular endothelial cell migration and tubulogenesis

Annabi B., Rojas-Sutterlin S., Laroche M., Lachambre MP., Moumdjian R. & Béliveau R.

Mesenchymal stromal cell–derived CCL2 suppresses plasma cell immunoglobulin production via STAT3 inactivation and PAX5 induction

Rafei M., Hiseh J., Fortier S., Li M, Yuan S., Birman E., Forner K., Boivin MN., Doody K, Tremblay M., Annabi B. & Galipeau J.

Inhibition of cancer cell proliferation and suppression of TNF-induced activation of NFkB by edible berry juice

Boivin D, Blanchette M, Barrette S, Moghrabi A and Béliveau R

Les jus de fruits rouges (canneberge, framboise, mûre) inhibent significativement NF-κB — un facteur clé de l'inflammation pro-tumorale — dans des cellules cancéreuses humaines.

VEGF increases the fibrinolytic activity of endothelial cells within fibrin matrices: Involvement of VEGFR-2, tPA and matrix metalloproteinases

Ratel D, Mihoubi S, Beaulieu E, Durocher Y, Rivard GE, Gingras D and Béliveau R

The role of nutrition in cancer prevention

Béliveau R and Gingras D

Article de synthèse pour les médecins de famille : l'alimentation peut réduire jusqu'à 35% le risque de cancer grâce à des composés phytochimiques spécifiques.

Towards a global assessment of the anticancer properties of fruits and vegetables: The Montreal anticancer nutrinome project

Gingras D and Béliveau R

Necrosis induction in glioblastoma cells reveals a new “bioswitch” function for the MT1-MMP/G6PT signaling axis in proMMP-2 activation versus death cell decision

Belkaid A., Fortier S., Cao J. & Annabi B.

Inhibition of HuR and MMP-9 expression in macrophage-differentiated HL-60 myeloid leukemia cells by green tea polyphenol EGCg

Annabi B., Currie JC., Moghrabi A. & Béliveau R.

Inhibition of HuR and MMP-9 expression in macrophage-differentiated HL-60 myeloid leukemia cells by green tea polyphenol EGCg Leukemia Research 31(9):1285-1292.

Annabi B, Currie JC, Moghrabi A and Béliveau R

The survivin-mediated radioresistant phenotype of glioblastomas is regulated by RhoA and inhibited by the green tea polyphenol (-) epigallocatechin-3-gallate

McLaughlin N, Annabi B, Bouzeghrane M, Temme A, Bahary JP, Moumdjian R and Béliveau R

Delphinidin, a dietary anthocyanidin, inhibits vascular endothelial growth factor receptor-2 phosphorylation

Lamy S, Blanchette M, Michaud-Levesque J, Lafleur R, Durocher Y, Moghrabi A, Barrette S, Gingras D, Béliveau R

The inhibition of MMP-9 secretion by anti-metastatic PSP94-derived peptide PCK3145 requires cell surface laminin receptors signalling

Annabi B, Bouzeghrane M, Currie JC, Dulude H, Daigneault L. Garde S, Rabbani SA, Panchal C, Wu JJ and Béliveau R

Combined low dose ionizing radiation and green tea-derived epigallocatechin-3-gallate treatment induces human brain endothelial cells death

McLaughlin N, Annabi B, Lachambre MP, Kim HS, Bahary JP, Moumdjian R and Béliveau R

Conferone from Ferula Schtschurowskiana enhances vinblastine cytotoxicity in MDCK-MDR1 cells by competitively inhibiting P-glycoprotein transport

Barthomeuf C, Demeule M, Grassi J, Saidkhodjaev A and Béliveau R

Anthocyanidins inhibit migration of glioblastoma cells : structure-activity relationship and involvement of the plasminolytic system

Lamy S, Lafleur R, Bédard V, Moghrabi A, Barrette S, Gingras D and Béliveau R

In vivo inhibition of angiogenesis by a soluble form of melanotransferrin

Michaud-Levesque J, Demeule M and Béliveau R

Can foods combat cancer ? Arresting malignancies with diet

Béliveau R, Gingras D

Lebectin, a Macrovipera lebetina venom-derived C-type lectin, inhibits both in vitro and in vivo angiogenesis

Pilorget A, Conesa M, Sarray S, Michaud-Levesque J, Daoud S, Kim KS, Demeule M, Marvaldi J, El Ayeb M, Marrakchi N, Béliveau R and Luis J

A prostate secretory protein94-derived synthetic peptide PCK3145 inhibits VEGF signalling in endothelial cells: Implication in tumor angiogenesis

Lamy S., Ruiz M., Wisniewski J., Garde S., Panchal C., Rabbani SA., Wu JJ. & Annabi B.

Silencing of the human microsomal glucose-6-phosphate translocase induces glioma cell death: Potential new anticancer target for curcumin

Belkaid A., Copland IB., Massillon D. & Annabi B.

La curcumine cible G6PT (glucose-6-phosphate translocase), une protéine surexprimée dans les cellules cancéreuses résistantes aux médicaments conventionnels.

Dietary prevention of cancer: Anticancer and Antiangiogenic Properties of Green Tea Polyphenols

Demeule M, Annabi B, Michaud-Lévesque J, Lamy S and Béliveau R

Direct-acting fibrinolytic enzymes in shark cartilage extract: Potential therapeutic role in vascular disorders

Ratel D, Glazier G, Provençal M, Boivin D, Beaulieu E, Gingras D, and Béliveau

Combined inhibition of PDGF end VEGF receptors by ellagic acid, a dietary-derived phenolic compound

Labrecque L, Lamy S, Chapus A, Mihoubi S, Durocher Y, Cass B, Bojanowski MW, Gingras D and Béliveau R

L'acide ellagique (présent dans les framboises et grenades) bloque les récepteurs PDGF et VEGF, coupant ainsi l'approvisionnement sanguin des tumeurs.

Inhibition of P-glycoprotein transport function and reversion of MDR1 multidrug resistance by cnidiadin

Barthomeuf C, Grassi J, Demeule M, Fournier C, Boivin D and Béliveau R

Membrane type 1-matrix metalloproteinase induces endothelial cell morphogenic differentiation by a caspase-dependent mechanism

Langlois S, Di Tomasso G, Boivin D, Roghi C, Murphy G, Gingras D and Béliveau R

Probing the infiltrating character of brain tumors : Inhibition of RhoA/ROK-mediated CD44 cell surface shedding from glioma cells by the green tea catechin EGCg

Annabi B, Bouzeghrane M, Moumdjian R, Moghrabi A and Béliveau R

Inhibition of sphingosine-1-phosphate- and vascular endothelial growth factor-induced endothelial cell chemotaxis by red grape skin polyphenols correlates with a down-regulation of PAF synthesis

Barthomeuf C, Lamy S, Blanchette M, Boivin D, Gingras D and Béliveau R

The antiangiogenic agent Neovastat (AE-941) stimulates tissue plasminogen activator activity

Gingras D, Labelle D, Carine N, Boivin D, Demeule M, Barthomeuf C and Béliveau R

Induction of medulloblastoma cell apoptosis by sulforaphane, a dietary anticarcinogen from Brassica vegetables

Gingras D, Gendron M, Boivin D, Moghrabi A, Théoret Y and Béliveau R

Green tea: prevention and treatment of cancer by nutraceuticals

Béliveau R and Gingras D

Publication historique dans The Lancet : le thé vert (EGCG) agit comme agent nutraceutique anticancer en inhibant la formation de vaisseaux tumoraux.

Diallyl dusulfide a chemopreventive agent in garlic induces multidrug-resistance associated protein 2 expression Biochem Biophys Res Comm 324: 937-945.

Demeule M, Brossard M, Turcotte S, Regina A, Jodoin J, Béliveau R

Purification and characterization of a stimulator of plasmin generation from the antiangiogenic agent Neovastat: identification as immunoglobulin Kappa light chain

Boivin D, Provençal M, Gendron S, Ratel D, Demeule M, Gingras D, and Béliveau R

Inhibition of HUVEC tubulogenesis by hederacolchiside-A1 is associated with plasma membrane cholesterol sequestration and activation of Ha-Ras/MEK/ERK cascade

Barthomeuf C, Boivin D, Béliveau R