This site is inspired by the work of David Servan-Schreiber and scientific literature on nutrition and cancer prevention. It does not replace medical advice and does not constitute a treatment.
Studies from Dr. Béliveau's laboratory and his team on anti-cancer nutrition
Akla N, Boudah A, Bertomeu T, Chatr-aryamontri A, Desjarlais M, ANNABI B. — Redox Biology 90:104047
A CRISPR study revealing the exact cellular targets of EGCG: green tea exploits redox imbalances specific to cancer cells, while sparing healthy cells.
103 publications found
Fallah A, Zgheib A, Danalache BA, Eliopoulos N, ANNABI B.
Study published in Biochemical and Biophysical Research Communications 794:153050 on the activity of dietary compounds in the context of brain.
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Akla N, Boudah A, Bertomeu T, Chatr-aryamontri A, Desjarlais M, ANNABI B.
A CRISPR study revealing the exact cellular targets of EGCG: green tea exploits redox imbalances specific to cancer cells, while sparing healthy cells.
Exploiting redox vulnerabilities of cancer cells via EGCG
Payet-Desruisseaux M, Zgheib A, Danalache BA, Desjarlais M, ANNABI B.
Study published in Exploration of Targeted Anti-tumor Therapy 2026;7:1002364 on the activity of dietary compounds in the context of brain.
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Veilleux C, Khalifa J, Zgheib A, Konan AS, Gaudreault R, ANNABI B.
Study published in Current Research in Pharmacology and Drug Discovery on the activity of dietary compounds in the context of breast, brain.
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Pepin SK, Zgheib A, Roy ME, ANNABI B.
Quercetin (found in onions) targets triple-negative breast cancer cells — the most aggressive subtype — by blocking the TGF-β pathway involved in metastasis.
Targeting triple-negative cancer cells via TGF-β
Roy ME, Zgheib A, Eliopoulos N, ANNABI B.
Study published in BMC Cancer on the activity of dietary compounds in the context of brain.
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Zilinski R, Konan AS, Zgheib A, Eliopoulos N, Boudreau LH, ANNABI B.
Study published in Cell Communication and Signaling 23:434 on the activity of dietary compounds in the context of brain.
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Fallah A, Payet-Desruisseaux M, Zgheib A, Danalache BA, Eliopoulos N, ANNABI B.
EGCG specifically targets glioblastoma stem cells — the most treatment-resistant — by blocking their oncogenic survival pathways.
Targeting oncogenic pluripotency in glioblastoma
Konan AS, Zilinski R, Tadrous M, Zgheib A, Gaudreault R, ANNABI B.
Study published in Journal of Inflammation Research 18 : 17523–17535 on the activity of dietary compounds in the context of brain.
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Roy ME, Veilleux C, Paquin A, Gagnon A, ANNABI B.
Study published in Anti-Cancer Drugs on the activity of dietary compounds in the context of brain, cancer in general.
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Akla N, Veilleux C, ANNABI B.
A review of the chemopreventive impact of phytochemicals: EGCG and other dietary compounds inhibit G6PT, a key metabolic target in cancer cells.
Chemopreventive impact of dietary phytochemicals on G6PT
Roy ME, Elimam R, Zgheib A, ANNABI B.
Study published in Journal of Cellular and Molecular Medicine on the activity of dietary compounds in the context of brain.
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Torabidastgerdooei S, Roy ME, ANNABI B.
Study published in Frontiers in Endocrinology 14 :1265698 on the activity of dietary compounds in the context of brain.
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Rodriguez Torres S, Gresseau L, Benhamida M, Fernandez-Marrero Y, ANNABI B.
Green tea EGCG prevents ovarian cancer cells from acquiring resistance to carboplatin (the standard chemotherapy), suggesting a therapeutic synergy.
Preventing drug resistance in ovarian cancer
Gonzalez Suarez N, Fernandez-Marrero Y, Hébert M, Roy ME, Boudreau LH, ANNABI B.
Study published in Cancer Cell International 23:240 on the activity of green tea in the context of breast.
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Hajjar R, Gonzalez E, Oliero M, Alaoui AA, Fragoso G, Calvé A, Vennin Rendos H, Djediai S, Cuisiniere T, Laplante P, Gerkins C, Ajayi AS, Diop K, Taleb N, Thérien S, Shampaert F, Alratrout H, Dagbert
Study published in Gut 72(6):1143-1154 on the activity of garlic in the context of colon.
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Kassouri C, Rodriguez Torres S, Gonzalez Suarez N, Duhamel S, ANNABI B.
Study published in Cancers 14(20):5065 on the activity of green tea in the context of leukemia.
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Gonzalez Suarez N, Fernandez-Marrero Y, Torabidastgerdooei S, ANNABI B.
Study published in Nutrients 14(5):1099 on the activity of green tea in the context of breast.
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Gresseau L, Roy ME, Duhamel S, ANNABI B
Study published in Cancers 14(23):5944 on the activity of garlic in the context of brain.
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Pratt J, Haidara K, ANNABI B
Study published in International Journal of Molecular Sciences 23(22):14214 on the activity of dietary compounds in the context of brain.
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Djediai S, Gonzalez Suarez N, El Cheikh-Hussein L, Rodriguez Torres S, Gresseau L, Dhayne S, Joly-Lopez Z, ANNABI B
Study published in International Journal of Molecular Sciences 22(23):13006 on the activity of garlic, omega-3 in the context of breast, brain.
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Sicard AA, Gonzalez Suarez N, Cappadocia L, ANNABI B
Study published in Journal of Nutritional Biochemistry 87:108518 on the activity of green tea in the context of ovarian.
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Sicard AA, Dao T, Suarez NG, ANNABI B
Study published in Nutrition and Cancer 73(1):169-180 on the activity of green tea in the context of ovarian.
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González Suárez N, Rodriguez Torres S, Ouanouki A, El Cheikh-Hussein L, ANNABI B
Study published in Molecules 26(6):1506 on the activity of green tea in the context of breast.
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Uthamacumaran A, Gonzalez Suarez N, Baniré Diallo A, ANNABI B
Study published in Cancer Informatics 20:1-8 on the activity of green tea in the context of cancer in general.
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Hajjar R, Oliero M, Cuisiniere T, Fragoso G, Calvé A, Djediai S, ANNABI B, Richard CS, Santos MM
Study published in Clinical Nutrition 40(6):3842-3851 on the activity of dietary compounds in the context of colon.
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Dao T, Salahuddin S, Charfi C, Sicard AA, Jenabian MA, ANNABI B
Study published in PharmaNutrition 12:100191 on the activity of green tea in the context of leukemia.
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Martin AC, Tomasin R, Luna-Dulcey L, Graminha AE, Naves MA, Gomes Teles RH, da Silva VD, da Silva JA, Vieira PC, ANNABI B, Cominetti MR
Study published in Cellular Oncology 43(5):915-929 on the activity of ginger in the context of breast, cancer in general.
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Ouanouki A., Lamy S., Annabi B.
Study published in Oncotarget, 2018, Vol on the activity of dietary compounds in the context of brain.
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Djerir D, Iddir M, Bourgault S, Lamy S, Annabi B
Study published in Biophysical Chemistry 234 :34–41 on the activity of green tea in the context of cancer in general.
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Lamy S, Muhire É, Annabi B.
Study published in J Funct Foods on the activity of berries in the context of brain.
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Annabi B, Zgheib A, Annabi B.
Study published in Int J Stem Cells on the activity of dietary compounds in the context of cancer in general.
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Ouanouki A, Lamy S, Annabi B.
Study published in Mol Carcinog on the activity of dietary compounds in the context of brain.
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Nanni SB, Pratt J, Beauchemin D, Haidara K, Annabi B.
Study published in Biomark Cancer on the activity of dietary compounds in the context of brain.
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Lamy S, Ben Saad A, Zgheib A, Annabi B.
The phenolic compounds in olive oil (oleocanthal, hydroxytyrosol) inhibit COX-2 in human glioblastoma cells — a mechanism similar to ibuprofen.
Inhibition of COX-2 and the inflammatory cascade in glioblastoma
Pratt J, Iddir M, Bourgault S, Annabi B.
Study published in Mol Carcinog on the activity of dietary compounds in the context of brain.
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Pratt A, Coady M, Annabi B.
Study published in Autophagy: Cancer, other pathologies, inflammation, immunity, infection, and aging on the activity of dietary compounds in the context of brain.
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Lamy S, Moldovan PL, Ben Saad A, Annabi B.
Study published in Biochim Biophys Acta 1853:126-135 on the activity of dietary compounds in the context of brain.
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Toufaily C, Charfi C, Annabi B, Annabi B.
Study published in Cancer Growth Metastasis on the activity of garlic in the context of cancer in general.
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Chokor R, Lamy S, Annabi B
Study published in Onco Targets Ther 7:667-677. on the activity of green tea in the context of leukemia.
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Pratt J, Annabi B.
Study published in Cell Signal on the activity of dietary compounds in the context of brain.
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Lamy S, Ouanouki A, Béliveau R, Desrosiers RR.
Olive polyphenols block VEGFR-2, the main receptor involved in forming the new blood vessels that feed tumors.
Inhibition of the VEGFR-2 receptor (anti-angiogenesis)
Desjarlais M, Pratt J, Lounis A, Mounier C, Haidara K, Annabi B
Study published in Gene Regul Syst Bio on the activity of omega-3 in the context of cancer in general.
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Vézina A, Vaillancourt-Jean E, Albarao S, Annabi B
Study published in Cancer Lett on the activity of garlic in the context of cancer in general.
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Annabi B., Vaillancourt-Jean, E., Béliveau R.
Study published in Inflammopharmacology 21(1):91-99 on the activity of garlic in the context of brain.
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Zgheib A, Lamy S, Annabi B.
Study published in J Biol Chem 288 (19):13378-86 on the activity of green tea in the context of colon.
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Vézina A, Chokor R, Annabi B.
Study published in Cancer Immunol Immunother on the activity of green tea in the context of leukemia.
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Pratt J, Roy R, Annabi B.
Study published in Glycobiology on the activity of dietary compounds in the context of brain.
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Lamy S, Akla N, Ouanouki A, Lord-Dufour S, Béliveau R
Study published in Experimental Cell Research 318:1586-1596 on the activity of dietary compounds in the context of cancer in general.
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Annabi B, Lord-Dufour S, Vézina A, Béliveau R
Study published in Drug Target Insights 2012:6 1-11 on the activity of resveratrol in the context of brain.
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Michaud-Levesque J, Bousquet-Gagnon N, Béliveau R
Study published in Exp Cell Res 318(8):925-35. on the activity of onion in the context of brain.
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Gingras D, Beliveau R
A comprehensive review of colorectal cancer prevention through diet: cruciferous vegetables, berries and green tea act on the tumor microenvironment to prevent progression.
Colorectal prevention by remodeling the tumor microenvironment
Proulx-Bonneau S., Pratt J. & Annabi B.
Study published in Journal of Neurooncology 104(1):33-43 on the activity of dietary compounds in the context of brain.
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Tahanian T., Arguello-Sanchez L., Shiao TC., Roy R. & Annabi B.
Study published in Drug Design, Development and Therapy 5:299-309 on the activity of dietary compounds in the context of brain.
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Tahanian E., Peiro S. & Annabi B.
Study published in Journal of Inflammation Research 4(1):1-10 on the activity of dietary compounds in the context of brain.
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Perry MC, Demeule M, Régina A, Moumdjian R, Béliveau R
Curcumin causes significant regression of glioblastoma xenografts in mice, paving the way for clinical trials in neuro-oncology.
Tumor regression via NF-κB inhibition and apoptosis induction
Nyalendo C, Sartelet H, Gingras D, Béliveau R
Study published in Anticancer Research 2010; 30:1887-1896 on the activity of dietary compounds in the context of cancer in general.
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Lamy S, Lachambre M-P, Lord-Dufour S, Béliveau R
Study published in Vascular Pharmacology 53(2010) 200-208 on the activity of dietary compounds in the context of cancer in general.
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Annabi B, Vaillancourt-Jean E, Weil AG & Béliveau R
Study published in N/A on the activity of garlic in the context of brain.
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Sina A., Proulx-Bonneau S., Roy A., Poliquin L., Cao J. & Annabi B.
Study published in Journal of Cell Communication and Signaling 4(1):31-38 on the activity of dietary compounds in the context of cancer in general.
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Annabi B, Lachambre MP, Plouffe K, Sartelet H & Béliveau R
Study published in N/A on the activity of dietary compounds in the context of brain.
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Annabi B, Laflamme C, Sina A, Lachambre MP, Béliveau R
Study published in Journal of Neuroinflammation 6(1):8 on the activity of dietary compounds in the context of brain.
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Labbé D, Provençal M, Lamy S, Boivin D, Gingras D and Béliveau R
Study published in Nutr on the activity of onion, omega-3 in the context of brain.
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Provençal M, Labbé D, Veitch R, Boivin D, Rivard G-E, Sartelet H, Robitaille Y, Gingras D and Béliveau R
Study published in Carcinogenesis 2009 30: 1089-1096 on the activity of garlic in the context of brain.
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Provençal M, Labbé D, Veitch R, Boivin D, Rivard GE, Gingras D, Béliveau R
Study published in Journal of Neurooncol on the activity of dietary compounds in the context of brain.
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Boivin D, Labbé D, Fontaine N, Lamy S, Beaulieu E, Gingras D, Béliveau R
Study published in Biochemistry on the activity of dietary compounds in the context of cancer in general.
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Boivin D, Lamy S, Lord-Dufour S, Jackson J, Beaulieu E, Côté M, Moghrabi A, Barrette S, Gingras D, Béliveau R
A comparative study: garlic, leek and onions show the strongest antiproliferative activity among common vegetables — confirming their central role in cancer prevention.
Inhibition of cell proliferation, antioxidant activity
Lamy S, Beaulieu E, Labbé D, Bédard V, Moghrabi A, Barrette S, Gingras D, Béliveau R
Delphinidin, an anthocyanidin from berries (blueberries, elderberry), inhibits the PDGF receptor, a key player in tumor growth and angiogenesis.
Inhibition of the PDGF receptor (anti-angiogenesis)
Barakat S, Turcotte S, Demeule M, Lachambre MP, Régina A, Baggetto LG, Béliveau R
Study published in Biochemical Biophysical Research Communications on the activity of dietary compounds in the context of brain.
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Lamy S, Bédard V, Sartelet H, Barthomeuf C, Gingras D, Béliveau R
Study published in Cancer Prev on the activity of dietary compounds in the context of cancer in general.
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Fortier S., Labelle D., Sina A., Moreau R. & Annabi B.
Study published in FEBS Letters 582(5):799-804 on the activity of dietary compounds in the context of brain.
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Annabi B., Rojas-Sutterlin S., Laroche M., Lachambre MP., Moumdjian R. & Béliveau R.
Study published in Molecular Nutrition and Food Research 52(6):692-700 on the activity of broccoli in the context of brain.
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Rafei M., Hiseh J., Fortier S., Li M, Yuan S., Birman E., Forner K., Boivin MN., Doody K, Tremblay M., Annabi B. & Galipeau J.
Study published in Blood 112(13):4991-4998 on the activity of dietary compounds in the context of skin.
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Boivin D, Blanchette M, Barrette S, Moghrabi A and Béliveau R
Berry juices (cranberry, raspberry, blackberry) significantly inhibit NF-κB — a key driver of pro-tumor inflammation — in human cancer cells.
NF-κB inhibition, anti-inflammatory and antiproliferative activity
Ratel D, Mihoubi S, Beaulieu E, Durocher Y, Rivard GE, Gingras D and Béliveau R
Study published in Thrombosis Research 121(2):203-212 on the activity of dietary compounds in the context of cancer in general.
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Béliveau R and Gingras D
A review article for family physicians: diet can reduce cancer risk by up to 35% thanks to specific phytochemical compounds.
Overview of dietary anti-cancer mechanisms
Gingras D and Béliveau R
Study published in Acta Hort on the activity of dietary compounds in the context of cancer in general.
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Belkaid A., Fortier S., Cao J. & Annabi B.
Study published in Neoplasia 9(4):332-340 on the activity of dietary compounds in the context of brain.
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Annabi B., Currie JC., Moghrabi A. & Béliveau R.
Study published in Leukemia Research 31(9):1285-1292 on the activity of green tea in the context of leukemia.
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McLaughlin N, Annabi B, Bouzeghrane M, Temme A, Bahary JP, Moumdjian R and Béliveau R
Study published in Brain Research on the activity of green tea in the context of brain.
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Lamy S, Blanchette M, Michaud-Levesque J, Lafleur R, Durocher Y, Moghrabi A, Barrette S, Gingras D, Béliveau R
Study published in Carcinogenesis2006 May;27 (5):989-996. on the activity of berries in the context of cancer in general.
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Annabi B, Bouzeghrane M, Currie JC, Dulude H, Daigneault L. Garde S, Rabbani SA, Panchal C, Wu JJ and Béliveau R
Study published in Anti-cancer Drugs 17(4): 429-438. on the activity of dietary compounds in the context of cancer in general.
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McLaughlin N, Annabi B, Lachambre MP, Kim HS, Bahary JP, Moumdjian R and Béliveau R
Study published in Journal of Neurooncology 80(2):111-121. on the activity of green tea in the context of brain.
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Barthomeuf C, Demeule M, Grassi J, Saidkhodjaev A and Béliveau R
Study published in Planta Med on the activity of dietary compounds in the context of cancer in general.
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Lamy S, Lafleur R, Bédard V, Moghrabi A, Barrette S, Gingras D and Béliveau R
Study published in J on the activity of dietary compounds in the context of brain.
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Michaud-Levesque J, Demeule M and Béliveau R
Study published in Carcinogenesis on the activity of dietary compounds in the context of cancer in general.
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Béliveau R, Gingras D
Study published in Oncology Exchange 5(3):31-34 Jul 2006. on the activity of dietary compounds in the context of cancer in general.
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Pilorget A, Conesa M, Sarray S, Michaud-Levesque J, Daoud S, Kim KS, Demeule M, Marvaldi J, El Ayeb M, Marrakchi N, Béliveau R and Luis J
Study published in Journal of Cellular Physiology 211:207-315, 2007. on the activity of dietary compounds in the context of cancer in general.
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Lamy S., Ruiz M., Wisniewski J., Garde S., Panchal C., Rabbani SA., Wu JJ. & Annabi B.
Study published in International Journal of Cancer 118(9):2350-2358 on the activity of dietary compounds in the context of prostate.
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Belkaid A., Copland IB., Massillon D. & Annabi B.
Curcumin targets G6PT (glucose-6-phosphate translocase), a protein overexpressed in cancer cells resistant to conventional drugs.
Inhibition of G6PT, an anti-cancer target in drug resistance
Demeule M, Annabi B, Michaud-Lévesque J, Lamy S and Béliveau R
Study published in Medicinal Chemistry Reviews2:49-58. on the activity of green tea in the context of cancer in general.
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Ratel D, Glazier G, Provençal M, Boivin D, Beaulieu E, Gingras D, and Béliveau
Study published in Thrombosis Res on the activity of dietary compounds in the context of cancer in general.
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Labrecque L, Lamy S, Chapus A, Mihoubi S, Durocher Y, Cass B, Bojanowski MW, Gingras D and Béliveau R
Ellagic acid (found in raspberries and pomegranates) blocks the PDGF and VEGF receptors, cutting off the tumors' blood supply.
Blocking the PDGF and VEGF receptors involved in angiogenesis
Barthomeuf C, Grassi J, Demeule M, Fournier C, Boivin D and Béliveau R
Study published in Cancer Chemotherapy and Pharmacology on the activity of dietary compounds in the context of cancer in general.
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Langlois S, Di Tomasso G, Boivin D, Roghi C, Murphy G, Gingras D and Béliveau R
Study published in Exp on the activity of dietary compounds in the context of cancer in general.
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Annabi B, Bouzeghrane M, Moumdjian R, Moghrabi A and Béliveau R
Study published in Journal of Neurochemistry 94:906-916. on the activity of green tea in the context of brain.
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Barthomeuf C, Lamy S, Blanchette M, Boivin D, Gingras D and Béliveau R
Study published in Free Rad on the activity of resveratrol in the context of skin.
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Gingras D, Labelle D, Carine N, Boivin D, Demeule M, Barthomeuf C and Béliveau R
Study published in Invest on the activity of dietary compounds in the context of cancer in general.
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Gingras D, Gendron M, Boivin D, Moghrabi A, Théoret Y and Béliveau R
Study published in Cancer Lett on the activity of broccoli in the context of brain.
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Béliveau R and Gingras D
A landmark publication in The Lancet: green tea (EGCG) acts as an anti-cancer nutraceutical by inhibiting the formation of tumor blood vessels.
Inhibition of tumor angiogenesis (anti-VEGF), apoptosis induction
Demeule M, Brossard M, Turcotte S, Regina A, Jodoin J, Béliveau R
Study published in N/A on the activity of garlic in the context of cancer in general.
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Boivin D, Provençal M, Gendron S, Ratel D, Demeule M, Gingras D, and Béliveau R
Study published in Arch on the activity of dietary compounds in the context of cancer in general.
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Barthomeuf C, Boivin D, Béliveau R
Study published in Cancer Chemother Pharmacol on the activity of dietary compounds in the context of cancer in general.
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